The Buffalo Bills’ all-time rushing yards leaders are topped by Hall of Fame running backs Thurman Thomas and O.J. Simpson. Thomas and Simpson each accumulated more than 10,000 rushing yards in a Bills’ uniform to place both in the top 20 in NFL history.
5. Wray Carlton: 3,368 yards
A member of two Bills’ championship teams in the 1960s, Wray Carlton remains fifth on the list of Buffalo Bills’ all-time rushing yards leaders. Carlton spent his entire eight-year career in Buffalo from 1960 to 1967, averaging 4.1 yards per carry and reaching the end zone 29 times. The two-time Pro Bowler led the league in rushing touchdowns with six in 1965 and he reached a career-high 696 yards in 1966.
4. Travis Henry: 3,849 yards
Travis Henry was a Pro Bowl running back for Buffalo in the first half of the 2000s and he left fourth on the Bills’ all-time rushing yards leaders list. Henry joined the Bills in the 2001 NFL Draft and he quickly became their primary rusher. He had back-to-back 1,000-yard seasons in 2002 and 2003, topping out with 1,438 rushing yards in 2002. Henry scored 27 touchdowns on the ground with two more receiving TDs in 54 games with the Bills.
3. Joe Cribbs: 4,445 yards
Three-time Pro Bowl running back Joe Cribbs ranks third among the Buffalo Bills’ all-time rushing yards leaders. Cribbs led the Bills’ backfield in the first half of the 1980s, posting three years of better than 1,000 yards on the ground. He earned his first Pro Bowl selection as a rookie with 1,185 rushing yards and 11 rushing touchdowns in 1980. Cribbs reached the end zone a combined 36 times via rushes and receptions for the Bills.
2. O.J. Simpson: 10,183 yards
Hall of Fame running back O.J. Simpson sits second on the list of Buffalo Bills’ all-time rushing yards leaders. Before leaving football for other endeavors, Simpson led the NFL in rushing yards four times. He was named an All-Pro five straight times from 1972 to 1976 and in 1973, he set a Bills’ single-season record with 2,003 rushing yards – the first 2,000 rushing yard season in NFL history. Simpson later set the Bills’ one-year record with 16 touchdown runs in 1975. His career total of 11,236 rushing yards ranks 18th in NFL history.
1. Thurman Thomas: 11,938 yards
The Buffalo Bills’ all-time rushing yards leader is Hall of Famer Thurman Thomas. Thomas spent 12 of his 13 NFL seasons in the Bills’ backfield en route to 12,074 career rushing yards, 14th most in NFL history. In 1991, he ran for 1,407 yards on a career best 4.9 yards per attempt to be named the NFL MVP. Thomas led the ground attack for the Bills as they reached an NFL record four consecutive Super Bowls, though they lost all four. From 1989 to 1996, he ran for more than 1,000 yards eight straight times. He added 4,341 receiving yards and a combined 88 touchdowns on the ground and in the air.
Buffalo Bills Rushing Career Register. Pro-Football-Reference.com